The M40 was shut between junction 2 and 3 after police, firefighters and ambulances attend an incident involving a silver car.
The incident happened going northbound from Beaconsfield to Loudwater.
All lanes have now reopened but the incident has caused a backlog of traffic.
An update from Bucks Fire said says after establishing that no-one was trapped the crew from Beaconsfield fire station handed the incident over to South Central Ambulance.
The update reads: "One appliance and crew from Beaconsfield attended. No-one was trapped. The incident was left with South Central Ambulance Service."
The latest updates for traffic on M40:
#M40 northbound between J2 (Gerrards Cross / Uxbridge) and J3 (Beaconsfield) - Congestion - Full details at https://t.co/pVheKmta94 (Updated every 5 minutes)
— Live Traffic - M40 (@Traffic_M40) July 25, 2021
Our reporter Stephanie Wareham who drive past the incident said: "There was a silver car that was sideways facing the grass verge and I think there was a silver minibus that was involved as well.
"There was one fire engine, loads of police and there were ambulances coming as well."
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